The application of aluminum foil in pharmaceutical packaging includes aluminum-plastic blister packaging (PTP), strip packaging, aluminum-plastic combined bottle caps, aluminum-plastic sealing gaskets and double aluminum packaging, of which ptp blister packaging is its main application, with moisture-proof, hygienic , safety, convenience and other advantages, thus becoming a new type of pharmaceutical packaging widely used in the world.
Pharmaceutical blister (PTP) packaging is to place the drug in the blister of the the blister-formed plastic hard sheet, and then a piece of blister aluminium foil that has been printed and coated with a protective agent is heat-sealed with the hard plastic sheet. The main materials of blister packaging are PTP aluminum foil, plastic hard sheet (polyvinyl chloride PVC) and adhesive.
Pharmaceutical PTP aluminum foil is non-toxic, odorless, and is of light weight, excellent shading properties, high moisture resistance and barrier properties. Aluminum foil for medicine packaging can be divided into hard aluminum foil and soft aluminum foil. The former is mostly used for blister packaging of tablets and capsules, while the latter is generally used for outer packaging of powder and granules.
Since the cold stamping forming hard sheet needs to be stamped and formed, the thickness of the aluminum foil used is much thicker than that of the ordinary composite film. Generally, a 45μm thick aluminum foil is used. For the occasion of stamping into a shallow bubble, the thickness of the aluminum foil can be appropriately reduced. Generally, the minimum thickness is 30μm. For the application of stamping into a particularly deep bubble (≥15mm), or the application of cold stamping hard sheet with better stiffness, the thickness of the aluminum foil can be increased appropriately, and the thickness can be increased to 70μm.
At present, there are three main types of aluminum foil used for pharmaceutical packaging, namely 8079 aluminum foil, 8021 aluminum foil, and 8011 aluminum foil. The three mainly have a little difference in metal element content and thickness.
8011 aluminum foil, also known as PTP aluminum foil, has a thickness of 0.016-0.04mm, high silicon content, and contains manganese and iron, which has high strength and corrosion resistance. It is often used in the packaging of medicine capsules or the back of medicine plates in pharmaceutical packaging. It is also used for the packaging of bottled liquids (such as antibiotics, infusion and other drug bottle caps).
8021 aluminum foil, also known as aluminum blister foil, has a thickness of 0.04mm-0.065mm, and is often used for the packaging of light-shielding medicines or moisture-proof medicines. The price of 8079 aluminum foil is high, compared with 8011 and 8021 aluminum foil, so its application is relatively less.
The way to make pharmaceutical aluminum foil packaging is to print and coat the aluminum foil on a special machine. During the production process, some quality problems such as pinholes, uneven thickness, poor surface printing quality, and low heat-sealing strength occurred. It is necessary to formulate strict material inspection methods and systems in order to improve the quality of raw materials and products. Welcome to leave message to inquire blister aluminium foil specification.