Pharmaceutical Foil for Blister Packaging

Pharmaceutical foil has become an important component of medicine packaging. The aluminum foil packaging can control the dose. Whether it is taken by itself or according to the doctor's order, the aluminum-plastic blister packaging can provide an accurate dose. The pharmaceutical packaging aluminum foils are usually 8011, 8021, 8079,etc.

High-sealing tropical packaging aluminum is a packaging material with high sealing, moisture-proof, anti-drug volatilization and anti-ultraviolet radiation used in high-grade drugs such as anti-inflammatory drugs.

Tropical medicinal aluminum foil is also called aluminum plastic aluminum, which is equivalent to adding a layer of cold stamping aluminum foil cover on the outside of thermoformed plastic blister and PTP aluminum foil. 8021-O and 8079-O are often used.

In addition to the function of barrier properties, the intermediate aluminum foil layer used in cold stamping also has functions such as strength support and resistance to stamping and stretching, so it is different from the general aluminum foil for flexible packaging.

The aluminum foil used in cold stamping is with extremely high strength and good extensibility. Since the cold stamped hard sheet needs to be stamped and formed, the thickness of the aluminum foil used is also much thicker than that of the ordinary composite film, generally 45μm.

Aluminum foil, especially thin aluminum foil, inevitably has various defects, and pinholes are the most important one. The size and number of pinholes are one of the important metrics to measure the quality level of aluminum foil.

The surface of the aluminum foil is allowed to have pinholes visible to the naked eye, but the pinholes shall not be densely arranged, and the diameter of the pinholes of the medicinal aluminum foil shall not be greater than 0.3 mm, and shall not exceed 5/m2.

During use of blister foil packaging, if its inherent quality is poor, foil breakage and rupture will often occur in production, thus affecting the printing and coating. The testing instrument is a burst strength tester. The method is to take three pieces of 40mm x 40mm samples from the finished product, put them in the gap of the instrument one by one, turn on the oil pump, and measure the indicated value on the pressure gauge. The burst strength should be greater than 98Kpa.

The standard thickness of medicine aluminum foil is 0.02 ± 0.002 mm. The thickness detection is often to check the thickness and width of the aluminum foil before putting it on the machine. Thickness detection is measured with a microcard or LG-l optical thickness meter with an accuracy of 0.5-1.0 um.